• Since not everyone has enough of the necessary enzymatic activity necessary to convert folic acid to 5-MTHF (the active form of folate), this highly potent dose of 5-MTHF makes it easier for you to get all the health benefits of the B vitamin folate. Indeed, you get 8500 mcg of dietary folate equivalents in every tablet.
• High Potency Optimized Folate helps maintain already normal levels of homocysteine, an important marker of heart health, and is also good for your brain health—specifically, maintaining healthy cognition.
• This heart and brain health supplement is also gluten-free, non-GMO and vegetarian. 

Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that's necessary to convert folic acid to 5-MTHF. A more useful approach is to take 5-MTHF directly. 

5-MTHF, homocysteine & cardiovascular health

Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker.And 5-MTHF has been shown to be more bioavailable than folic acid in some studies. 

5-MTHF, homocysteine & cognitive health

5-MTHF's greater bioavailability is especially important for people who don't have enough activity of the enzyme necessary to convert folic acid to its biologically active form. Since people with elevated homocysteine levels have a greater risk of cognitive decline, the increased efficiency of 5-MTHF in supporting healthy folate status is especially crucial for aging individuals. 

Take alone or with B12 for enhanced effect

The RDA for folate for non-pregnant or lactating adults is 400 mcg a day, but this high-potency formula provides 8500 mcg of this super-bioavailable form of folate. For even greater health benefits, take 5-MTHF folate with methylcobalamin (the active form of vitamin B12), vitamin B6 and/or riboflavin. 

• High potency – This powerful folate supplement contains 8500 mcg of 5-MTHF folate, the bioactive form of folic acid. Choosing 5-MTHF instead of regular folic acid is a good option because not everyone can convert folate to 5-MTHF.
• Cardiovascular support – Folate is a heart-healthy B vitamin. Why? Folate helps maintain normal levels of homocysteine, a metabolic byproduct. Keeping homocysteine levels within normal range is an important biomarker for cardiovascular health.
• Cognitive health – Folate is also a “big brain” vitamin: it helps maintain cognitive health. Again, this has to do with keeping homocysteine levels within normal range, as homocysteine has also been associated with normal cognitive decline.
• Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.?
• Live your healthiest life - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. That’s why so many of our nutritional formulas are designed using specific ingredients and amounts based on scientific studies. 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.